Área Reproductiva

Grupo de Investigación en Infertilidad Masculina y estimulación embrionaria

José Remohí Giménez

El Dr. Remohí estudió Medicina en la Universitat de València obteniendo la Licenciatura en 1981, se doctoró en 1986 por la misma Universidad y realizó la especialidad de Obstetricia y Ginecología en el Hospital Clínico Universitario de Valencia. En la Universidad de Irvine –California-, se especializó en Endocrinología Obstétrica Reproductiva. Además, es médico maternólogo desde 1984  y sexólogo desde 1986.

Fundó el Instituto Valenciano de Infertilidad (IVI) en 1990 junto al Profesor Pellicer, y su trabajo en el campo de la reproducción ha conducido a la creación de clínicas IVI tanto en España como internacionalmente. También es presidente del Comité Ético de IVI desde agosto de 1995 y director del Instituto Univeristario IVI

Es Catedrático de Obstetricia y Ginecología en la Universitat de València desde 2006 así como director de Máster de Cirugía Endoscópica ginecológica avanzada de esta universidad.

Miembro de reconocidas sociedades como la Sociedad Española de Fertilidad (SEF), European Society of Human Reproduction and Embriology (ESHRE), The American Fertility Society, FIGO Expert Advisory Panel on Reproductive Medicine, SOLAMER o la Asociación Española de Andrología (ASESA).

El Profesor Remohí es autor de 8 libros de medicina reproductiva, ha escrito 200 capítulos de libros relacionados con la reproducción humana y ha publicado más de 400 artículos en revistas nacionales e internacionales. Además, ha presentado alrededor de 400 conferencias en congresos por todo el mundo.

También es revisor de las prestigiosas revistas como Human Reproduction, Ferililty & Sterility, RB Monlines, Boletines Técnicos de la SEGO, Cuadernos de Medicina Reproductiva entre otras. De ésta última igualmente es miembro de su consejo editorial, como lo es de la Revista de la Asociación Colombiana de Fertilidad, la Revista Ciencia Ginecológica y la Revista de Obstetricia y Ginecología de Postgrado.

Ha obtenido diferentes premios por su contribución al campo de la salud reproductiva, donde cabe destacar los siguientes: Annual Meeting Prize Paper concedido en siete ocasiones por la American Society for Reproductive Medicine, Premio Ares-Serono Foundation (Suiza, 1997), Premios de investigación de la SEF (España 1987, 1996, 1998, 2000, 2002 y 2004).

Otros premios de reconocimiento social: Premio Protagonistas Onda Cero a la mejor trayectoria científica (2002, España), Premio Investigación Club Rotarios (2003, España), Premio Investigación Economía 3 (España, 2004).

 

Investigadora colaboradora

Amparo Ruiz Jorro
Carmen Rubio Lluesa
Inmaculada Campos Galindo
Mª del Carmen Vidal Martínez
Tamara Viloria Samochín

Investigador colaborador

Jaime Ferro Camargo
Jose Antonio Martínez Conejero
José María de los Santos Molina
Juan Giles Jiménez

Investigadora predoctoral

Lorena Rodrigo Vivó
Rocío Rivera Egea
  • Los resultados han puesto de manifiesto una disminución, estadísticamente significativa, de la frecuencia de recombinación meiótica en el grupo de pacientes con azoospermia secretora comparado con el grupo control (45,2 vs. 48,7; p< 0,0001). En el grupo de pacientes con azoospermia secretora que inicialmente eran criptozoospérmicos no se observa esta disminución de forma significativa (48,7 vs.  49,1; p= 0,3763). También se ha realizado la medición de la longitud los complejos sinaptonémicos de 264 células en estadio de paquitene en el grupo control y en el grupo de estudio un total de 111 células. No se han observado diferencias estadísticamente significativas
  • En cuanto al estudio de respiración seminal, en la anualidad 2013 se recogieron las muestras susceptibles de participar en el mismo según los criterios de inclusión, y se relacionaron con los resultados obtenidos de la prueba β-hCG clasificándolas en grupos de muestras que consiguen embarazo (β-hCG +) y grupo de muestras que no lo hace (β-hCG -).
Número total de publicaciones: 143. Factor de Impacto acumulado: 619.55
Assessment of embryo morphology and developmental dynamics by time-lapse microscopy: is there a relation to implantation and ploidy?
Zaninovic N, Irani M, Meseguer M
Fertility and sterility. 2017 Nov. 722-729. FI: 4.447
Effect of oocyte vitrification on embryo quality: time-lapse analysis and morphokinetic evaluation.
Cobo A, Coello A, Remohí J, Serrano J, de Los Santos JM, Meseguer M
Fertility and sterility.. 2017 Sep. 491-497.e3. FI: 4.447
Individual luteolysis pattern after GnRH-agonist trigger for final oocyte maturation
Lawrenz B, Garrido N, Samir S, Ruiz F, Melado L, Fatemi HM
Plos One. 2017 May 1. e0176600. FI: 2.806
Obstetric and perinatal outcome of babies born from sperm selected by MACS from a randomized controlled trial
Romany L, Garrido N, Cobo A, Aparicio-Ruiz B, Serra V, Meseguer M
Journal of assisted reproduction and genetics. 2017 Feb. 201-207. FI: 1.718
Obstetric and perinatal outcomes of pregnancies conceived with embryos cultured in a time-lapse monitoring system
Insua MF, Cobo AC, Larreategui Z, Ferrando M, Serra V, Meseguer M
Fertility and sterility. 2017 Sep. 498-504. FI: 4.447
Reproductive outcomes of testicular versus ejaculated sperm for intracytoplasmic sperm injection among men with high levels of DNA fragmentation in semen: systematic review and meta-analysis
Esteves SC, Roque M, Bradley CK, Garrido N
Fertility and sterility. 2017 Sep. 456-467. FI: 4.447
The most well kept secret, embryo culture media: a smart reveal from an expert
Meseguer M, Pellicer A
Fertility and sterility. 2017 Apr. 910. FI: 4.447
Type of chromosome abnormality affects embryo morphology dynamics.
Del Carmen Nogales M, Bronet F, Basile N, Martínez EM, Liñán A, Rodrigo L, Meseguer M
Fertility and sterility.. 2017 Jan. 229-235.e2. FI: 4.447
What else can we do? The latest attempt to improve the sperm's path
Meseguer M, Pellicer A
Fertility and sterility. 2017 Sep. 444-445. FI: 4.447
What the human sperm methylome tells us
Camprubí C, Cigliano RA, Salas-Huetos A, Garrido N, Blanco J
Epigenomics. 2017 Oct. 1299-1315. FI: 4.541
Pregnancy, Hormonal Treatments for Infertility, Contraception, and Menopause in Women After Ischemic Stroke: A Consensus Document.
Caso V, Falorni A, Bushnell CD, Acciarresi M, Remohí J, Sprigg N, Gerli S.
Stroke. 2017 Feb. 501-506. FI: 6.032
Assessing the true incidence of mosaicism in preimplantation embryos.
Vera-Rodriguez M, Rubio C.
Fertility and sterility. 2017 May. 1107-1112. FI: 4.447
The use of morphokinetic as a predictor of implantation
Tejera A, Aparicio-Ruiz B, Meseguer M.
Minerva ginecologica. 2017 Dec. 555-567
Clinical use of sperm DNA fragmentation analysis results, a practical example of how to deal with too much information from the literature in reproductive medicine
Garrido N, Rivera R, Luján S.
Translational andrology and urology. 2017 Sep. S547-S548
Analysis of the morphological dynamics of blastocysts after vitrification/warming: defining new predictive variables of implantation.
Coello A, Meseguer M, Galán A, Alegre L, Remohí J, Cobo A
Fertility and sterility.. 2017 Oct. 659-666. FI: 4.447
Paving the way for a gold standard of care for infertility treatment: improving outcomes through standardization of laboratory procedures.
Schoolcraft W, Meseguer M, Global Fertility Alliance. Electronic address: alan.thornhill@igenomix.com.
Reproductive biomedicine online.. 2017 Oct. 391-399. FI: 2.89
One for all or all for one? The evolution of embryo morphokinetics.
Meseguer M, Pellicer A
Fertility and sterility.. 2017 Mar. 571-572. FI: 4.447
New protocol based on massive parallel sequencing for aneuploidy screening of preimplantation human embryos
Vendrell X, Fernández-Pedrosa V, Triviño JC, Bautista-Llácer R, Collado C, Rodríguez O, García-Mengual E, Ferrer E, Calatayud C, Ruiz-Jorro M.
Systems biology in reproductive medicine. 2017 Jun. 162-178. FI: 1.176
Low serum progesterone on the day of embryo transfer is associated with a diminished ongoing pregnancy rate in oocyte donation cycles after artificial endometrial preparation: a prospective study
Labarta E, Mariani G, Holtmann N, Celada P, Remohí J, Bosch E.
Human reproduction. 2017 Dec 1. 2437-3442. FI: 5.02
In vitro fertilization with preimplantation genetic diagnosis for aneuploidies in advanced maternal age: a randomized, controlled study.
Rubio C, Bellver J, Rodrigo L, Castillón G, Guillén A, Vidal C, Giles J, Ferrando M, Cabanillas S, Remohí J, Pellicer A, Simón C.
Fertility and sterility. 2017 May. 1122-1129. FI: 4.447
Time-lapse: the remaining questions to be answered.
Meseguer M
Fertility and sterility.. 2016 Feb. 295-6. FI: 4.447
Automatic time-lapse instrument is superior to single-point morphology observation for selecting viable embryos: retrospective study in oocyte donation.
Aparicio-Ruiz B, Basile N, Pérez Albalá S, Bronet F, Remohí J, Meseguer M
Fertility and sterility.. 2016 Nov. 1379-1385.e10. FI: 4.447
Combination of metabolism measurement and a time-lapse system provides an embryo selection method based on oxygen uptake and chronology of cytokinesis timing.
Tejera A, Castelló D, de Los Santos JM, Pellicer A, Remohí J, Meseguer M
Fertility and sterility.. 2016 Jul. 119-126.e2. FI: 4.447
Detection of Missing Proteins Using the PRIDE Database as a Source of Mass Spectrometry Evidence.
Garin-Muga A, Odriozola L, Martínez-Val A, Del Toro N, Martínez R, Molina M, Cantero L, Rivera R, Garrido N, Dominguez F, Sanchez Del Pino MM, Vizcaíno JA, Corrales FJ, Segura V
Journal of proteome research.. 2016 Nov 4. 4101-4115. FI: 4.173
Evidence that the endometrial microbiota has an effect on implantation success or failure.
Moreno I, Codoñer FM, Vilella F, Valbuena D, Martinez-Blanch JF, Jimenez-Almazán J, Alonso R, Alamá P, Remohí J, Pellicer A, Ramon D, Simon C
American journal of obstetrics and gynecology.. 2016 Dec. 684-703. FI: 5.226
How much have we learned from time-lapse in clinical IVF?
Castelló D, Motato Y, Basile N, Remohí J, Espejo-Catena M, Meseguer M
Molecular human reproduction.. 2016 Oct. 719-727. FI: 3.943
Spermatozoa from infertile patients exhibit differences of DNA methylation associated with spermatogenesis-related processes: an array-based analysis.
Camprubí C, Salas-Huetos A, Aiese-Cigliano R, Godo A, Pons MC, Castellano G, Grossmann M, Sanseverino W, Martin-Subero JI, Garrido N, Blanco J
Reproductive biomedicine online.. 2016 Dec. 709-719. FI: 2.796
Spermatozoa from normozoospermic fertile and infertile individuals convey a distinct miRNA cargo.
Salas-Huetos A, Blanco J, Vidal F, Grossmann M, Pons MC, Garrido N, Anton E
Andrology.. 2016 Nov. 1028-1036. FI: 2.515
Study of nucleation status in the second cell cycle of human embryo and its impact on implantation rate.
Aguilar J, Rubio I, Muñoz E, Pellicer A, Meseguer M
Fertility and sterility.. 2016 Aug. 291-299.e2. FI: 4.447
The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists
Sermon K, Capalbo A, Cohen J, Coonen E, De Rycke M, De Vos A, Delhanty J, Fiorentino F, Gleicher N, Griesinger G, Grifo J, Handyside A, Harper J, Kokkali G, Mastenbroek S, Meldrum D, Meseguer M, Montag M, Munné S, Rienzi L, Rubio C, Scott K, Scott R, Simon C, Swain J, Treff N, Ubaldi F, Vassena R, Vermeesch JR, Verpoest W, Wells D, Geraedts J
Molecular human reproduction. 2016 Aug. 845-57. FI: 3.943
A combination of hydroxypropyl cellulose and trehalose as supplementation for vitrification of human oocytes: a retrospective cohort study.
Coello A, Campos P, Remohí J, Meseguer M, Cobo A
Journal of assisted reproduction and genetics.. 2016 Mar. 413-21. FI: 1.718
Angiotensin II type 2 receptor is expressed in human sperm cells and is involved in sperm motility.
Gianzo M, Muñoa-Hoyos I, Urizar-Arenaza I, Larreategui Z, Quintana F, Garrido N, Subirán N, Irazusta J
Fertility and sterility.. 2016 Mar. 608-16. FI: 4.447
Autologous cell therapy with CD133+ bone marrow-derived stem cells for refractory Asherman's syndrome and endometrial atrophy: a pilot cohort study.
Santamaria X, Cabanillas S, Cervelló I, Arbona C, Raga F, Ferro J, Palmero J, Remohí J, Pellicer A, Simón C
Human reproduction. 2016 May. 1087-96. FI: 5.02
Blastocyst development in single medium with or without renewal on day 3: a prospective cohort study on sibling donor oocytes in a time-lapse incubator.
Costa-Borges N, Bellés M, Meseguer M, Galliano D, Ballesteros A, Calderón G
Fertility and sterility.. 2016 Mar. 707-13. FI: 4.447
Confirmation rates of array-CGH in day-3 embryo and blastocyst biopsies for preimplantation genetic screening.
Mir P, Mateu E, Mercader A, Herrer R, Rodrigo L, Vera M, Peinado V, Milán-Sánchez M, Campos-Galindo I, García-Herrero S, Simón C, Rubio C
Journal of assisted reproduction and genetics.. 2016 Jan. 59-66. FI: 1.718
Correlations between Synaptic Initiation and Meiotic Recombination: A Study of Humans and Mice.
Gruhn JR, Al-Asmar N, Fasnacht R, Maylor-Hagen H, Peinado V, Rubio C, Broman KW, Hunt PA, Hassold T
American journal of human genetics.. 2016 Jan 7. 102-15. FI: 10.931
Distribution patterns of segmental aneuploidies in human blastocysts identified by next-generation sequencing.
Vera-Rodríguez M, Michel CE, Mercader A, Bladon AJ, Rodrigo L, Kokocinski F, Mateu E, Al-Asmar N, Blesa D, Simón C, Rubio C
Fertility and sterility.. 2016 Apr. 1047-1055.e2. FI: 4.59
Genetic Analysis of Human Preimplantation Embryos.
Garcia-Herrero S, Cervero A, Mateu E, Mir P, Póo ME, Rodrigo L, Vera M, Rubio C
Current topics in developmental biology.. 2016. 421-47. FI: 4.677
Impact of vitrification on the mitochondrial activity and redox homeostasis of human oocyte.
Nohales-Córcoles M, Sevillano-Almerich G, Di Emidio G, Tatone C, Cobo AC, Dumollard R, De Los Santos Molina MJ
Journal of the British Fertility Society.. 2016 May 31. . FI: 4.621
Morphokinetic analysis and embryonic prediction for blastocyst formation through an integrated time-lapse system.
Motato Y, de Los Santos MJ, Escriba MJ, Ruiz BA, Remohí J, Meseguer M
Fertility and sterility.. 2016 Feb. 376-384.e9. FI: 4.447
Oocyte vitrification as an efficient option for elective fertility preservation.
Cobo A, García-Velasco JA, Coello A, Domingo J, Pellicer A, Remohí J
Fertility and sterility.. 2016 Mar. 755-764.e8. FI: 4.59
Optimizing the culture environment and embryo manipulation to help maintain embryo developmental potential.
Swain JE, Carrell D, Cobo A, Meseguer M, Rubio C, Smith GD
Fertility and sterility.. 2016 Mar. 571-87. FI: 4.447
Comprehensive carrier genetic test using next-generation deoxyribonucleic acid sequencing in infertile couples wishing to conceive through assisted reproductive technology
Martin J, Asan, Yi Y, Alberola T, Rodríguez-Iglesias B, Jiménez-Almazán J, Li Q, Du H, Alama P, Ruiz A, Bosch E, Garrido N, Simon C
Fertility and sterility. 2015 Nov. 1286-93. FI: 4.59
Collapse of blastocysts is strongly related to lower implantation success: a time-lapse study.
Marcos J, Pérez-Albalá S, Mifsud A, Molla M, Landeras J, Meseguer M
Journal of the British Fertility Society.. 2015 Nov. 2501-8. FI: 4.569
Diagnosis of human preimplantation embryo viability.
Gardner DK, Meseguer M, Rubio C, Treff NR
Human reproduction update.. 2015 Nov-Dec. 727-47. FI: 10.165
Difference in birth weight of consecutive sibling singletons is not found in oocyte donation when comparing fresh versus frozen embryo replacements.
Galliano D, Garrido N, Serra-Serra V, Pellicer A
Fertility and sterility.. 2015 Dec. 1411-1418.e3. FI: 4.59
Doubtful association between progesterone therapy and fetal nuchal translucency.
Serra V, Bellver J, Garrido N
American journal of obstetrics and gynecology.. 2015 Sep. 437. FI: 4.704
Is there a relationship between time-lapse parameters and embryo sex?
Bronet F, Nogales MC, Martínez E, Ariza M, Rubio C, García-Velasco JA, Meseguer M
Fertility and sterility. 2015 Feb. 396-401.e2. FI: 4.59
Mitochondrial DNA content as a viability score in human euploid embryos: less is better.
Diez-Juan A, Rubio C, Marin C, Martinez S, Al-Asmar N, Riboldi M, Díaz-Gimeno P, Valbuena D, Simón C
Fertility and sterility.. 2015 Sep. 534-41.e1. FI: 4.59
Molecular analysis of products of conception obtained by hysteroembryoscopy from infertile couples.
Campos-Galindo I, García-Herrero S, Martínez-Conejero JA, Ferro J, Simón C, Rubio C
Journal of assisted reproduction and genetics. 2015 May. 839-48. FI: 1.718
Morphokinetics as a predictor of self-correction to diploidy in tripronucleated intracytoplasmic sperm injection-derived human embryos.
Grau N, Escrich L, Galiana Y, Meseguer M, García-Herrero S, Remohí J, Escribá MJ
Fertility and sterility.. 2015 Sep. 728-35. FI: 4.59
New strategy for diagnosing embryo implantation potential by combining proteomics and time-lapse technologies.
Dominguez F, Meseguer M, Aparicio-Ruiz B, Piqueras P, Quiñonero A, Simón C
Fertility and sterility.. 2015 Oct. 908-14. FI: 4.59
Oocyte donation outcome after oncological treatment in cancer survivors.
Muñoz E, Fernandez I, Martinez M, Tocino A, Portela S, Pellicer A, García-Velasco JA, Garrido N
Fertility and sterility. 2015 Jan. 205-13. FI: 4.59
Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis.
Vera-Rodriguez M, Chavez SL, Rubio C, Pera RA, Simon C
Nature communications. 2015 Jul 7. 7601. FI: 11.47
Prenatal diagnosis of 24 cases of microduplication 22q11.2: an investigation of phenotype-genotype correlations.
Dupont C, Grati FR, Choy KW, Jaillard S, Toutain J, Maurin ML, Martínez-Conejero JA, Beneteau C, Coussement A, Molina-Gomes D, Horelli-Kuitunen N, Aboura A, Tabet AC, Besseau-Ayasse J, Bessieres-Grattagliano B, Simoni G, Ayala G, Benzacken B, Vialard F
Prenatal diagnosis. 2015 Jan. 35-43. FI: 3.268
Six years' experience in ovum donation using vitrified oocytes: report of cumulative outcomes, impact of storage time, and development of a predictive model for oocyte survival rate.
Cobo A, Garrido N, Pellicer A, Remohí J
Fertility and sterility.. 2015 Dec. 1426-1434.e8. FI: 4.59
Sperm selection in natural conception: what can we learn from Mother Nature to improve assisted reproduction outcomes?
Sakkas D, Ramalingam M, Garrido N, Barratt CL
Human reproduction update.. 2015 Nov-Dec. 711-26. FI: 10.165
Spermatozoa from patients with seminal alterations exhibit a differential micro-ribonucleic acid profile.
Salas-Huetos A, Blanco J, Vidal F, Godo A, Grossmann M, Pons MC, F-Fernández S, Garrido N, Anton E
Fertility and sterility.. 2015 Sep. 591-601. FI: 4.59
Systematic review on clinical outcomes following selection of human preimplantation embryos with time-lapse monitoring.
Freour T, Basile N, Barriere P, Meseguer M
Human reproduction update. 2015 Jan. 153-4. FI: 10.165
The Metabolomic Profile of Spent Culture Media from Day-3 Human Embryos Cultured under Low Oxygen Tension.
de Los Santos MJ, Gámiz P, de Los Santos JM, Romero JL, Prados N, Alonso C, Remohí J, Dominguez F
PLoS hub for clinical trials. 2015. e0142724. FI: 3.234
The necessity to define the sub-optimal responders.
Garcia-Velasco JA, Bosch E
Journal of the British Fertility Society.. 2015 Dec. 2958. FI: 4.569
The time to prevent mendelian genetic diseases from donated or own gametes has come.
Garrido N, Bosch E, Alamá P, Ruiz A
Fertility and sterility.. 2015 Oct. 833-5. FI: 4.59
The use of morphokinetics as a predictor of ?implantation: a multicentric study to define and validate an algorithm for embryo selection.
Basile N, Vime P, Florensa M, Aparicio Ruiz B, García Velasco JA, Remohí J, Meseguer M
Human reproduction (Oxford, England). 2015 Feb. 276-83. FI: 4.569
Time-lapse in the IVF lab: how should we assess potential benefit?
Basile N, Barrière P, Meseguer M, Fréour T
Human reproduction (Oxford, England). 2015 May. 1276. FI: 4.569
Transcriptome of early embryonic invasion at implantation sites in a murine model.
Moreno-Moya JM, Franchi NA, Martínez-Escribano S, Martínez-Conejero JA, Bocca S, Oehninger S, Horcajadas JA
Sexual health.. 2015 May 5. . FI: 2.4
Understanding Mammalian Germ Line Development with In Vitro Models.
Martínez-Arroyo AM, Míguez-Forján JM, Remohí J, Pellicer A, Medrano JV
Stem cells and development.. 2015 Sep 15. 2101-13. FI: 3.727
What does morphokinetics add to embryo selection and in-vitro fertilization outcomes?
Basile N, Caiazzo M, Meseguer M
Current opinion in obstetrics & gynecology. 2015 Jun. 193-200. FI: 2.067
BACs-on-Beads technology: a reliable test for rapid detection of aneuploidies and microdeletions in prenatal diagnosis.
García-Herrero S, Campos-Galindo I, Martínez-Conejero JA, Serra V, Olmo I, Lara C, Simón C, Rubio C
BioMed research international. 2014. 590298
Next-generation sequencing: challenges in reproductive genetics.
Rubio C
Fertility and sterility. 2014 May. 1252-3. FI: 4.295
The human first cell cycle: impact on implantation.
Aguilar J, Motato Y, Escribá MJ, Ojeda M, Muñoz E, Meseguer M
Reproductive biomedicine online. 2014 Apr. 475-84. FI: 3.015
Clinical validation of embryo culture and selection by morphokinetic analysis: a randomized, controlled trial of the EmbryoScope.
Rubio I, Galán A, Larreategui Z, Ayerdi F, Bellver J, Herrero J, Meseguer M
Fertility and sterility. 2014 Nov. 1287-1294.e5. FI: 4.59
Increasing the probability of selecting chromosomally normal embryos by time-lapse morphokinetics analysis.
Basile N, Nogales Mdel C, Bronet F, Florensa M, Riqueiros M, Rodrigo L, García-Velasco J, Meseguer M
Fertility and sterility. 2014 Mar. 699-704. FI: 4.59
Germ cell transplantation into mouse testes procedure.
Medrano JV, Martínez-Arroyo AM, Sukhwani M, Noguera I, Quiñonero A, Martínez-Jabaloyas JM, Pellicer A, Remohí J, Orwig KE, Simón C
Fertility and sterility. 2014 Oct. e11-2. FI: 4.295
Effect of ischemic postconditioning on microvascular obstruction in reperfused myocardial infarction. Results of a randomized study in patients and of an experimental model in swine.
Bodi V, Ruiz-Nodar JM, Feliu E, Minana G, Nunez J, Husser O, Martinez-Elvira J, Ruiz A, Bonanad C, Monmeneu JV, Lopez-Lereu MP, Forteza MJ, de Dios E, Hervas A, Moratal D, Gomez C, Mainar L, Sanchis J, Mainar V, Valencia J, Diaz A, Noguera I, Chaustre F, Chorro FJ
International journal of cardiology. 2014 Jul 15. 138-46. FI: 6.175
In the secretory endometria of women, luminal epithelia exhibit gene and protein expressions that differ from those of glandular epithelia.
Evans GE, Martínez-Conejero JA, Phillipson GT, Sykes PH, Sin IL, Lam EY, Print CG, Horcajadas JA, Evans JJ
Fertility and sterility. 2014 Jul. 307-317.e7. FI: 4.295
Germ line development: lessons learned from pluripotent stem cells.
Martínez-Arroyo AM, Medrano JV, Remohí J, Simón C
Current opinion in genetics & development. 2014 Oct. 64-70. FI: 8.568
Ethnicity as a determinant of ovarian reserve: differences in ovarian aging between Spanish and Indian women.
Iglesias C, Banker M, Mahajan N, Herrero L, Meseguer M, Garcia-Velasco JA
Fertility and sterility. 2014 Jul. 244-9. FI: 4.59
New insights into the expression profile and function of micro-ribonucleic acid in human spermatozoa.
Salas-Huetos A, Blanco J, Vidal F, Mercader JM, Garrido N, Anton E
Fertility and sterility. 2014 Jul. 213-222.e4. FI: 4.59
High progesterone levels in women with high ovarian response do not affect clinical outcomes: a retrospective cohort study.
Requena A, Cruz M, Bosch E, Meseguer M, García-Velasco JA
Reproductive biology and endocrinology : RB&E. 2014 Jul 26. 69. FI: 2.226
New tools for embryo selection: comprehensive chromosome screening by array comparative genomic hybridization.
Rodrigo L, Mateu E, Mercader A, Cobo AC, Peinado V, Milán M, Al-Asmar N, Campos-Galindo I, García-Herrero S, Mir P, Simón C, Rubio C
BioMed research international. 2014. 517125
Obstetric and perinatal outcome of babies born from vitrified oocytes.
Cobo A, Serra V, Garrido N, Olmo I, Pellicer A, Remohí J
Fertility and sterility. 2014 Oct. 1006-1015.e4. FI: 4.59
Spanish Mediterranean diet and other dietary patterns and breast cancer risk: case-control EpiGEICAM study.
Castelló A, Pollán M, Buijsse B, Ruiz A, Casas AM, Baena-Cañada JM, Lope V, Antolín S, Ramos M, Muñoz M, Lluch A, de Juan-Ferré A, Jara C, Jimeno MA, Rosado P, Díaz E, Guillem V, Carrasco E, Pérez-Gómez B, Vioque J, Boeing H, Martín M
British journal of cancer. 2014 Sep 23. 1454-62. FI: 4.817
Removal of annexin V-positive sperm cells for intracytoplasmic sperm injection in ovum donation cycles does not improve reproductive outcome: a controlled and randomized trial in unselected males.
Romany L, Garrido N, Motato Y, Aparicio B, Remohí J, Meseguer M
Fertility and sterility. 2014 Dec. 1567-1575.e1. FI: 4.59
Maternal KIR haplotype influences live birth rate after double embryo transfer in IVF cycles in patients with recurrent miscarriages and implantation failure.
Alecsandru D, Garrido N, Vicario JL, Barrio A, Aparicio P, Requena A, García-Velasco JA
Human reproduction (Oxford, England). 2014 Dec. 2637-43. FI: 4.569
A time to look back: analysis of morphokinetic characteristics of human embryo development.
Herrero J, Tejera A, Albert C, Vidal C, de los Santos MJ, Meseguer M
Fertility and sterility. 2013 Dec. 1602-9.e1-4. FI: 4.295
Acadesine for patients with relapsed/refractory chronic lymphocytic leukemia (CLL): a multicenter phase I/II study.
Van Den Neste E, Cazin B, Janssens A, González-Barca E, Terol MJ, Levy V, Pérez de Oteyza J, Zachee P, Saunders A, de Frias M, Campàs C
Cancer chemotherapy and pharmacology. 2013 Mar. 581-91. FI: 2.795
Additive effect of factors related to assisted conception on the reduction of maternal serum pregnancy-associated plasma protein A concentrations and the increased false-positive rates in first-trimester Down syndrome screening.
Bellver J, Casanova C, Garrido N, Lara C, Remohí J, Pellicer A, Serra V
Fertility and sterility. 2013 Nov. 1314-20. FI: 4.295
Age-associated telomere shortening in mouse oocytes.
Yamada-Fukunaga T, Yamada M, Hamatani T, Chikazawa N, Ogawa S, Akutsu H, Miura T, Miyado K, Tarín JJ, Kuji N, Umezawa A, Yoshimura Y
Reproductive biology and endocrinology : RB&E. 2013 Nov 21. 108. FI: 2.144
The impact of coffee on health.
Cano-Marquina A, Tarín JJ, Cano A
Maturitas. 2013 May. 44378. FI: 2.844
Is vitrification of oocytes useful for fertility preservation for age-related fertility decline and in cancer patients?
Cobo A, Garcia-Velasco JA, Domingo J, Remohí J, Pellicer A
Fertility and sterility. 2013 May. 1485-95. FI: 4.174
Are physicians underestimating the challenges of hypertension management? Results from the Supporting Hypertension Awareness and Research Europe-wide (SHARE) survey.
Erdine S, Redon J, Böhm M, Ferri C, Kolloch R, Kreutz R, Laurent S, Persu A, Schmieder RE, SHARE Steering Committee
European journal of preventive cardiology. 2013 Oct. 786-92
Use of array comparative genomic hybridization (array-CGH) for embryo assessment: clinical results.
Rubio C, Rodrigo L, Mir P, Mateu E, Peinado V, Milán M, Al-Asmar N, Campos-Galindo I, Garcia S, Simón C
Fertility and sterility. 2013 Mar 15. 1044-8. FI: 4.174
Assessment of sperm using mRNA microarray technology.
Garrido N, García-Herrero S, Meseguer M
Fertility and sterility. 2013 Mar 15. 1008-22. FI: 4.295
Selection of high potential embryos using time-lapse imaging: the era of morphokinetics.
Herrero J, Meseguer M
Fertility and sterility. 2013 Mar 15. 1030-4. FI: 4.295
The type of GnRH analogue used during controlled ovarian stimulation influences early embryo developmental kinetics: a time-lapse study.
Muñoz M, Cruz M, Humaidan P, Garrido N, Pérez-Cano I, Meseguer M
European journal of obstetrics, gynecology, and reproductive biology. 2013 Jun. 167-72. FI: 1.627
Type of culture media does not affect embryo kinetics: a time-lapse analysis of sibling oocytes.
Basile N, Morbeck D, García-Velasco J, Bronet F, Meseguer M
Human reproduction (Oxford, England). 2013 Mar. 634-41. FI: 4.585
Similar morphokinetic patterns in embryos derived from obese and normoweight infertile women: a time-lapse study.
Bellver J, Mifsud A, Grau N, Privitera L, Meseguer M
Human reproduction (Oxford, England). 2013 Mar. 794-800. FI: 4.585
Effect of vitrification on human oocytes: a metabolic profiling study.
Dominguez F, Castello D, Remohí J, Simón C, Cobo A
Fertility and sterility. 2013 Feb. 565-572.e3. FI: 4.174
Filling the void about sperm function knowledge and how the -omics approach can close the circle.
Garrido N
Fertility and sterility. 2013 Aug. 349-50. FI: 4.295
Gene expression in amygdala as a function of differential trait anxiety levels in genetically heterogeneous NIH-HS rats.
Díaz-Morán S, Palència M, Mont-Cardona C, Cañete T, Blázquez G, Martínez-Membrives E, López-Aumatell R, Sabariego M, Donaire R, Morón I, Torres C, Martínez-Conejero JA, Tobeña A, Esteban FJ, Fernández-Teruel A
Behavioural brain research. 2013 Sep 1. 422-31. FI: 3.327
Incidence and predictors of ovarian function recovery (OFR) in breast cancer (BC) patients with chemotherapy-induced amenorrhea (CIA) who switched from tamoxifen to exemestane.
Guerrero A, Gavilá J, Folkerd E, Ortiz B, Martínez F, García A, Climent MA, Guillem V, Ruíz A
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 2013 Mar. 674-9. FI: 7.384
Impact of graft-versus-host disease prophylaxis on outcomes after myeloablative single-unit umbilical cord blood transplantation.
Sanz J, Picardi A, Hernández Boluda JC, Martín C, Ferrá C, Nozzoli C, Gonzalez-Vicent M, Rambaldi A, Valcarcel D, Verdeguer A, Serrano D, de Heredia CD, Pascual MJ, de Paz R, Montesinos P, Bartolozzi B, Algarotti A, Sanz MA, Arcese W, Sanz GF, GETH and GITMO
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2013 Sep. 1387-92. FI: 3.94
Short-term storage of tripronucleated human embryos.
Grau N, Aparicio B, Escrich L, Mercader A, Delgado A, Remohí J, Escribá MJ
Journal of assisted reproduction and genetics. 2013 Aug. 1043-7. FI: 1.823
Bed rest after embryo transfer negatively affects in vitro fertilization: a randomized controlled clinical trial.
Gaikwad S, Garrido N, Cobo A, Pellicer A, Remohi J
Fertility and sterility. 2013 Sep. 729-35. FI: 4.295
Incentive loss and hippocampal gene expression in inbred Roman high- (RHA-I) and Roman low- (RLA-I) avoidance rats.
Sabariego M, Morón I, Gómez MJ, Donaire R, Tobeña A, Fernández-Teruel A, Martínez-Conejero JA, Esteban FJ, Torres C
Behavioural brain research. 2013 Sep 18. 62-70. FI: 3.327
Obesity reduces uterine receptivity: clinical experience from 9,587 first cycles of ovum donation with normal weight donors.
Bellver J, Pellicer A, García-Velasco JA, Ballesteros A, Remohí J, Meseguer M
Fertility and sterility. 2013 Oct. 1050-1058.e2. FI: 4.295
Oocyte insemination techniques are related to alterations of embryo developmental timing in an oocyte donation model.
Cruz M, Garrido N, Gadea B, Muñoz M, Pérez-Cano I, Meseguer M
Reproductive biomedicine online. 2013 Oct. 367-75. FI: 2.98
Is morphokinetic analysis the answer?
Aparicio B, Cruz M, Meseguer M
Reproductive biomedicine online. 2013 Dec. 654-63. FI: 2.98
Outcome of cryotransfer of embryos developed from vitrified oocytes: double vitrification has no impact on delivery rates.
Cobo A, Castellò D, Vallejo B, Albert C, de Los Santos JM, Remohí J
Fertility and sterility. 2013 May. 1623-1630.e7. FI: 4.174
Lack of association of MTHFR rs1801133 polymorphism and CTCFL mutations with sperm methylation errors in infertile patients.
Camprubí C, Pladevall M, Grossmann M, Garrido N, Pons MC, Blanco J
Journal of assisted reproduction and genetics. 2013 Sep. 1125-31. FI: 1.772
Reduced oxygen tension improves embryo quality but not clinical pregnancy rates: a randomized clinical study into ovum donation cycles.
de los Santos MJ, Gámiz P, Albert C, Galán A, Viloria T, Pérez S, Romero JL, Remohï J
Fertility and sterility. 2013 Aug. 402-7. FI: 4.174
Prevalence and clinical characteristics of patients with true resistant hypertension in central and Eastern Europe: data from the BP-CARE study.
Brambilla G, Bombelli M, Seravalle G, Cifkova R, Laurent S, Narkiewicz K, Facchetti R, Redon J, Mancia G, Grassi G
Journal of hypertension. 2013 Oct. 2018-24. FI: 3.806
Pyelonephritis in pregnancy. How adequate is empirical treatment?
Artero A, Alberola J, Eiros JM, Nogueira JM, Cano A
Revista española de quimioterapia : publicación oficial de la Sociedad Española de Quimioterapia. 2013 Mar. 41728. FI: 0.836
Response to lenalidomide in myelodysplastic syndromes with del(5q): influence of cytogenetics and mutations.
Mallo M, Del Rey M, Ibáñez M, Calasanz MJ, Arenillas L, Larráyoz MJ, Pedro C, Jerez A, Maciejewski J, Costa D, Nomdedeu M, Diez-Campelo M, Lumbreras E, González-Martínez T, Marugán I, Such E, Cervera J, Cigudosa JC, Alvarez S, Florensa L, Hernández JM, Solé F
British journal of haematology. 2013 Jul. 74-86. FI: 4.942
Cytological studies of human meiosis: sex-specific differences in recombination originate at, or prior to, establishment of double-strand breaks.
Gruhn JR, Rubio C, Broman KW, Hunt PA, Hassold T
PloS one. 2013 Dec 20. e85075. FI: 3.73
Transobturator suburethral tape in the treatment of stress urinary incontinence: Efficacy and quality of life after 5 year follow up.
Cañete P, Ortiz E, Domingo S, Cano A
Maturitas. 2013 Feb. 166-71. FI: 2.844
Spanish Consensus Statement on alternatives to allogeneic blood transfusion: the 2013 update of the "Seville Document".
Leal-Noval SR, Muñoz M, Asuero M, Contreras E, García-Erce JA, Llau JV, Moral V, Páramo JA, Quintana M
Blood transfusion = Trasfusione del sangue. 2013 Oct. 585-610. FI: 1.858
PGE2 and PGF2? Concentrations in Human Endometrial Fluid as Biomarkers for Embryonic Implantation.
Vilella F, Ramirez L, Berlanga O, Martínez S, Alamá P, Meseguer M, Pellicer A, Simón C
The Journal of clinical endocrinology and metabolism. 2013 Oct. 4123-32. FI: 6.31
GnRH analogues for the treatment of fibroids.
Murillo EO, Cano A
Medicina clínica. 2013 Jul. 35-9. FI: 1.399
Testing the water before swimming: satisfying the need for clinical trials of devices, media, and instruments before their use in assisted reproduction laboratories.
Garrido N, Pellicer A, Niederberger C
Fertility and sterility. 2012 Feb. 245-6. FI: 4.174
Chromosomal abnormalities in embryos from couples with a previous aneuploid miscarriage.
Al-Asmar N, Peinado V, Vera M, Remohí J, Pellicer A, Simón C, Hassold T, Rubio C
Fertility and sterility. 2012 Jul. 145-50. FI: 4.174
Cumulative newborn rates increase with the total number of transferred embryos according to an analysis of 15,792 ovum donation cycles.
Garrido N, Bellver J, Remohí J, Alamá P, Pellicer A
Fertility and sterility. 2012 Aug. 341-346.e2. FI: 4.174
Consistent and predictable delivery rates after oocyte vitrification: an observational longitudinal cohort multicentric study.
Rienzi L, Cobo A, Paffoni A, Scarduelli C, Capalbo A, Vajta G, Remohí J, Ragni G, Ubaldi FM
Human reproduction (Oxford, England). 2012 Jun. 1606-12. FI: 4.67
Prenatal BACs-on-Beads™: the prospective experience of five prenatal diagnosis laboratories.
Vialard F, Simoni G, Gomes DM, Abourra A, De Toffol S, Bru F, Martinez Romero MC, Nitsch L, Bouhanna P, Marcato L, Popowski T, Grimi B, Martínez-Conejero JA, Benzacken B, Genesio R, Grati FR
Prenatal diagnosis. 2012 Apr. 329-35. FI: 2.683
Effect of adenomyosis on implantation.
Vila-Vives JM, Martínez-Conejero JA, Pellicer A
Reproductive biomedicine online. 2012 May. 584; author reply 585. FI: 2.675
Full in vitro fertilization laboratory mechanization: toward robotic assisted reproduction?
Meseguer M, Kruhne U, Laursen S
Fertility and sterility. 2012 Jun. 1277-86. FI: 4.174
Accumulation of oocytes: a new strategy for managing low-responder patients.
Cobo A, Garrido N, Crespo J, José R, Pellicer A
Reproductive biomedicine online. 2012 Apr. 424-32. FI: 2.675
Hepatitis B virus in human oocytes and embryos.
Garrido N, Bellver J, Rubio C, Pellicer A
Human reproduction (Oxford, England). 2012 Apr. 1227-8; author reply 1228-9. FI: 4.67
Gene and protein expression signature of endometrial glandular and stromal compartments during the window of implantation.
Evans GE, Martínez-Conejero JA, Phillipson GT, Simón C, McNoe LA, Sykes PH, Horcajadas JA, Lam EY, Print CG, Sin IL, Evans JJ
Fertility and sterility. 2012 Jun. 1365-73.e1-2. FI: 4.174
Hormonal and molecular characterization of follicular fluid, cumulus cells and oocytes from pre-ovulatory follicles in stimulated and unstimulated cycles.
de los Santos MJ, García-Láez V, Beltrán-Torregrosa D, Horcajadas JA, Martínez-Conejero JA, Esteban FJ, Pellicer A, Labarta E
Human reproduction (Oxford, England). 2012 Jun. 1596-605. FI: 4.67
Citicoline in the treatment of acute ischaemic stroke: an international, randomised, multicentre, placebo-controlled study (ICTUS trial).
Dávalos A, Alvarez-Sabín J, Castillo J, Díez-Tejedor E, Ferro J, Martínez-Vila E, Serena J, Segura T, Cruz VT, Masjuan J, Cobo E, Secades JJ, International Citicoline Trial on acUte Stroke (ICTUS) trial investigators
Lancet. 2012 Jul 28. 349-57. FI: 39.06
Identification and characterization of the human leiomyoma side population as putative tumor-initiating cells.
Mas A, Cervelló I, Gil-Sanchis C, Faus A, Ferro J, Pellicer A, Simón C
Fertility and sterility. 2012 Sep. 741-751.e6. FI: 4.174
In vitro production of haploid cells after coculture of CD49f+ with Sertoli cells from testicular sperm extraction in nonobstructive azoospermic patients.
Riboldi M, Rubio C, Pellicer A, Gil-Salom M, Simón C
Fertility and sterility. 2012 Sep. 580-590.e4. FI: 4.174
Time-dependent O2 consumption patterns determined optimal time ranges for selecting viable human embryos.
Tejera A, Herrero J, Viloria T, Romero JL, Gamiz P, Meseguer M
Fertility and sterility. 2012 Oct. 849-57.e1-3. FI: 4.174
Dose of recombinant FSH and oestradiol concentration on day of HCG affect embryo development kinetics.
Muñoz M, Cruz M, Humaidan P, Garrido N, Pérez-Cano I, Meseguer M
Reproductive biomedicine online. 2012 Oct. 382-9. FI: 2.675
Moderate ovarian stimulation does not increase the incidence of human embryo chromosomal abnormalities in in vitro fertilization cycles.
Labarta E, Bosch E, Alamá P, Rubio C, Rodrigo L, Pellicer A
The Journal of clinical endocrinology and metabolism. 2012 Oct. E1987-94. FI: 6.43
Embryo incubation and selection in a time-lapse monitoring system improves pregnancy outcome compared with a standard incubator: a retrospective cohort study.
Meseguer M, Rubio I, Cruz M, Basile N, Marcos J, Requena A
Fertility and sterility. 2012 Dec. 1481-1489.e10. FI: 4.174
Limited implantation success of direct-cleaved human zygotes: a time-lapse study.
Rubio I, Kuhlmann R, Agerholm I, Kirk J, Herrero J, Escribá MJ, Bellver J, Meseguer M
Fertility and sterility. 2012 Dec. 1458-63. FI: 4.174
Outcomes of vitrified early cleavage-stage and blastocyst-stage embryos in a cryopreservation program: evaluation of 3,150 warming cycles.
Cobo A, de Los Santos MJ, Castellò D, Gámiz P, Campos P, Remohí J
Fertility and sterility. 2012 Nov. 1138-1146.e1. FI: 4.174
Timing of cell division in human cleavage-stage embryos is linked with blastocyst formation and quality.
Cruz M, Garrido N, Herrero J, Pérez-Cano I, Muñoz M, Meseguer M
Reproductive biomedicine online. 2012 Oct. 371-81. FI: 2.675
The Role of LH in Ovarian Stimulation.
Munoz E, Bosch E, Fernandez I, Portela S, Ortiz G, Remohi J, Pellicer A
Current pharmaceutical biotechnology. 2012 Mar 1. 409-16. FI: 2.69
Viral screening of spent culture media and liquid nitrogen samples of oocytes and embryos from hepatitis B, hepatitis C, and human immunodeficiency virus chronically infected women undergoing in vitro fertilization cycles.
Cobo A, Bellver J, de Los Santos MJ, Remohí J
Fertility and sterility. 2012 Jan. 74-8. FI: 4.174
Semen samples showing an increased rate of spermatozoa with imprinting errors have a negligible effect in the outcome of assisted reproduction techniques.
Camprubí C, Pladevall M, Grossmann M, Garrido N, Pons MC, Blanco J
Epigenetics : official journal of the DNA Methylation Society. 2012 Oct. 1115-24. FI: 4.92

Diagnóstico genético ovocitario por análisis del primer corpúsculo polar

Referencia:
PI16/00687
Entidad financiadora:
Instituto de Salud Carlos III
Duración:
01/01/2017 - 31/12/2019
Presupuesto total:
€97.405

Estudio clínico del estrés oxidativo como biomarcador adicional de viabilidad embrionaria en fecundación in vitro combinado con la selección por morfocinética.

Referencia:
PI14/00523
Entidad financiadora:
Instituto de Salud Carlos III
Duración:
01/01/2015 - 31/12/2017
Presupuesto total:
€108.925

Development of new safety methods for fertility preservation in oncologic patients

Referencia:
PROMETEOII/2014/045
Entidad financiadora:
Conselleria de Educación, Cultura y Deporte
Duración:
01/01/2014 - 01/01/2017
Presupuesto total:
€135.755

Estudio de la respiración seminal como nuevo método diagnóstico del potencial fértil del varón mediante la microrespiración.

Referencia:
ACOMP/2013/045
Investigador/a principal:
Nicolás Garrido Puchalt
Entidad financiadora:
Conselleria de Educación, Cultura y Deporte
Duración:
01/01/2013 - 31/12/2013
Presupuesto total:
€11.628

Estudio de la respiración seminal como nuevo método diagnóstico del potencial fértil del varón mediante la microrespiración.

Referencia:
PI11/01077
Investigador/a principal:
Nicolás Garrido Puchalt
Entidad financiadora:
Instituto de Salud Carlos III
Duración:
01/01/2012 - 31/12/2014
Presupuesto total:
€27.291

Un año más, los investigadores de INCLIVA entre los mejores investigadores de Valencia

Según el ranking basado en el factor h elaborado por DIH, el Dr. Carlos Simón el segundo en el ranking de su especialidad en España.

Publicado el 11/01/2017.Leer más »