Investigacion

Carlos Ferrando Ortola

Carlos Ferrando Ortola
cafeort@gmail.com

Carlos Ferrando Ortola

 
Algunas de las líneas de investigación en curso en nuestro grupo son: 
1. Papel de los anestésicos en la respuesta inflamatoria en anestesia y pacientes críticos. 
2. Estrategias para optimizar e individualizar el manejo ventilatorio intraoperatorio (medicina de precisión).
3. Papel de las estrategias ventilatorias perioperatorias en las complicaciones postoperatorias. 
4. Papel del oxígeno suplementario perioperatorio en las complicaciones postoperatorias. 
Some of the ongoing research lines in our group are: 
1. Role of anaesthetics in the inflammatory response in anaesthesia and critical care patients. 
2. Strategies to optimize and individualize intraoperative ventilatory management (precision medicine). 
3. Role of the perioperative ventilatory strategies in postoperative complications. 
4. Role of perioperative supplemental oxygen in postoperative complications.
Número total de publicaciones: 31. Factor de Impacto acumulado: 98.93
Postural lung recruitment assessed by lung ultrasound in mechanically ventilated children
Tusman G, Acosta CM, Böhm SH, Waldmann AD, Ferrando C, Marquez MP, Sipmann FS.
Critical ultrasound journal. 2017 Oct 13. 22
Rationale and study design for an individualised perioperative open-lung ventilatory strategy with a high versus conventional inspiratory oxygen fraction (iPROVE-O2) and its effects on surgical site infection: study protocol for a randomised controlled tr
Ferrando C, Soro M, Unzueta C, Canet J, Tusman G, Suarez-Sipmann F, Librero J, Peiró S, Pozo N, Delgado C, Ibáñez M, Aldecoa C, Garutti I, Pestaña D, Rodríguez A, García Del Valle S, Diaz-Cambronero O, Balust J, Redondo FJ, De La Matta M, Gallego L, Granell M, Martínez P, Pérez A, Leal S, Alday K, García P, Monedero P, Gonzalez R, Mazzinari G, Aguilar G, Villar J, Belda FJ, iPROVE-O2 Network Group.
BMJ open.. 2017 Jul 31. e016765. FI: 2.369
WHO Needs High FIO2?
Akca O, Ball L, Belda FJ, Biro P, Cortegiani A, Eden A, Ferrando C, Gattinoni L, Goldik Z, Gregoretti C, Hachenberg T, Hedenstierna G, Hopf HW, Hunt TK, Pelosi P, Qadan M, Sessler DI, Soro M, Sentürk M.
Turkish journal of anaesthesiology and reanimation. 2017 Aug. 181-192
Open lung approach versus standard protective strategies: Effects on driving pressure and ventilatory efficiency during anesthesia - A pilot, randomized controlled trial.
Ferrando C, Suarez-Sipmann F, Tusman G, León I, Romero E, Gracia E, Mugarra A, Arocas B, Pozo N, Soro M, Belda FJ
PLoS hub for clinical trials. 2017. e0177399. FI: 3.057
New frontiers: art and innovation for intraoperative ventilatory management.
Ferrando C, Belda FJ
Minerva anestesiologica.. 2017 Jul 20. . FI: 1.729
Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in Europe
Habre W, Disma N, Virag K, Becke K, Hansen TG, Jöhr M, Leva B, Morton NS, Vermeulen PM, Zielinska M, Boda K, Veyckemans F; APRICOT Group of the European Society of Anaesthesiology Clinical Trial Network
The Lancet. Respiratory medicine. 2017 May. 412-425. FI: 19.287
A quantile analysis of plateau and driving pressures: effects on mortality in patients with acute respiratory distress syndrome receiving lung-protective ventilation.
Villar J, Martín-Rodríguez C, Domínguez-Berrot AM, Fernández L, Ferrando C, Soler JA, Díaz-Lamas AM, González-Higueras E, Nogales L, Ambrós A, Carriedo D, Hernández M, Martínez D, Blanco J, Belda J, Parrilla D, Suárez-Sipmann F, Tarancón C, Mora-Ordoñez JM, Blanch L, Pérez-Méndez L, Fernández RL, Kacmarek RM, Spanish Initiative for Epidemiology, Stratification and Therapies for ARDS (SIESTA) Investigators Network.
Critical care medicine.. 2017 May. 843-850. FI: 7.422
The accuracy of postoperative, non-invasive Air-Test to diagnose atelectasis in healthy patients after surgery: a prospective, diagnostic pilot study.
Ferrando C, Romero C, Tusman G, Suarez-Sipmann F, Canet J, Dosdá R, Valls P, Villena A, Serralta F, Jurado A, Carrizo J, Navarro J, Parrilla C, Romero JE, Pozo N, Soro M, Villar J, Belda FJ
BMJ open.. 2017 May 29. e015560. FI: 2.369
Personalized intraoperative PEEP: a further step in protective ventilation
Ferrando C, Belda FJ
Minerva anestesiologica. 2017 Sep 11. . FI: 1.729
Performance of the New Turbine Mid-Level Critical Care Ventilators.
Delgado C, Romero JE, Puig J, Izquierdo A, Ferrando C, Belda FJ, Soro M
Respiratory care.. 2017 Jan. 34-41. FI: 1.922
Age, PaO2/FIO2, and plateau pressure score: a proposal for a simple outcome score in patients with the acute respiratory distress syndrome.
Villar J, Ambrós A, Soler JA, Martínez D, Ferrando C, Solano R, Mosteiro F, Blanco J, Martín-Rodríguez C, Fernández MM, López J, Díaz-Domínguez FJ, Andaluz-Ojeda D, Merayo E, Pérez-Méndez L, Fernández RL, Kacmarek RM, Stratification and Outcome of Acute Respiratory Distress Syndrome (STANDARDS) Network.
Critical care medicine.. 2016 Jul. 1361-9. FI: 6.312
Evaluating the efficacy of dexamethasone in the treatment of patients with persistent acute respiratory distress syndrome: study protocol for a randomized controlled trial.
Villar J, Belda J, Añón JM, Blanco J, Pérez-Méndez L, Ferrando C, Martínez D, Soler JA, Ambrós A, Muñoz T, Rivas R, Corpas R, Díaz-Dominguez FJ, Soro M, García-Bello MA, Fernández RL, Kacmarek RM, DEXA-ARDS Network
Trials. 2016 Jul 22. 342. FI: 1.859
Neurally adjusted ventilatory assist in patients with acute respiratory failure: study protocol for a randomized controlled trial.
Villar J, Belda J, Blanco J, Suarez-Sipmann F, Añón JM, Pérez-Méndez L, Ferrando C, Parrilla D, Montiel R, Corpas R, González-Higueras E, Pestaña D, Martínez D, Fernández L, Soro M, García-Bello MA, Fernández RL, Kacmarek RM, NAVa In Acute respiraTORy failure (NAVIATOR) Network.
Trials. 2016 Oct 13. 500. FI: 1.859
Open Lung Approach for the Acute Respiratory Distress Syndrome: A Pilot, Randomized Controlled Trial.
Kacmarek RM, Villar J, Sulemanji D, Montiel R, Ferrando C, Blanco J, Koh Y, Soler JA, Martínez D, Hernández M, Tucci M, Borges JB, Lubillo S, Santos A, Araujo JB, Amato MB, Suárez-Sipmann F, Open Lung Approach Network
Critical care medicine.. 2016 Jan. 32-42. FI: 6.312
Accuracy of an autocalibrated pulse contour analysis in cardiac surgery patients: a bi-center clinical trial.
Broch O, Carbonell J, Ferrando C, Metzner M, Carstens A, Albrecht M, Gruenewald M, Höcker J, Soro M, Steinfath M, Renner J, Bein B
BMC anesthesiology. 2015 Nov 26. 171. FI: 1.375
Adjusting tidal volume to stress index in an open lung condition optimizes ventilation and prevents overdistension in an experimental model of lung injury and reduced chest wall compliance.
Ferrando C, Suárez-Sipmann F, Gutierrez A, Tusman G, Carbonell J, García M, Piqueras L, Compañ D, Flores S, Soro M, Llombart A, Belda F
Critical care (London, England). 2015 Jan 13. 9. FI: 5.035
Combined treatment with bexarotene and rosuvastatin reduces angiotensin-II-induced abdominal aortic aneurysm in apoE(-/-) mice and angiogenesis.
Escudero P, Navarro A, Ferrando C, Furio E, Gonzalez-Navarro H, Juez M, Sanz MJ, Piqueras L
British journal of pharmacology.. 2015 Jun. 2946-60. FI: 4.842
Epidemiology of invasive candidiasis in a surgical intensive care unit: an observational study.
Aguilar G, Delgado C, Corrales I, Izquierdo A, Gracia E, Moreno T, Romero E, Ferrando C, Carbonell JA, Borrás R, Navarro D, Belda FJ
BMC research notes. 2015 Sep 29. 491
Inverse ratio ventilation: back to the future?
Ferrando C, Belda FJ
Critical care medicine. 2015 Mar. 724-5. FI: 6.312
Protection strategies during cardiopulmonary bypass: ventilation, anesthetics and oxygen.
Ferrando C, Soro M, Belda FJ
Current opinion in anaesthesiology. 2015 Feb. 73-80. FI: 1.979
Rationale and study design for an individualized perioperative open lung ventilatory strategy (iPROVE): study protocol for a randomized controlled trial.
Ferrando C, Soro M, Canet J, Unzueta MC, Suárez F, Librero J, Peiró S, Llombart A, Delgado C, León I, Rovira L, Ramasco F, Granell M, Aldecoa C, Diaz O, Balust J, Garutti I, de la Matta M, Pensado A, Gonzalez R, Durán ME, Gallego L, Del Valle SG, Redondo FJ, Diaz P, Pestaña D, Rodríguez A, Aguirre J, García JM, García J, Espinosa E, Charco P, Navarro J, Rodríguez C, Tusman G, Belda FJ, iPROVE investigators (Appendices 1 and 2).
Trials. 2015 Apr 27. 193. FI: 1.731
The Effects of Flow Waveform on Oxygenation in Pediatric Patients.
Ferrando C, Belda FJ
Anesthesia and analgesia.. 2015 Oct. 1111. FI: 3.472
Anidulafungin dosing in critically ill patients with continuous venovenous haemodiafiltration.
Aguilar G, Azanza JR, Carbonell JA, Ferrando C, Badenes R, Parra MA, Sadaba B, Navarro D, Puig J, Miñana A, Garcia-Marquez C, Gencheva G, Gutierrez A, Marti FJ, Belda FJ
The Journal of antimicrobial chemotherapy. 2014 Jun. 1620-3. FI: 5.313
Pharmacokinetics of anidulafungin during albumin dialysis.
Aguilar G, Azanza JR, Sádaba B, Badenes R, Ferrando C, Delgado C, Hernández J, Parra MA, Puig J, Carbonell JA, Navarro D, Belda FJ
Critical care (London, England). 2014 Mar 31. 422
Effects of different flow patterns and end-inspiratory pause on oxygenation and ventilation in newborn piglets: an experimental study.
Ferrando C, García M, Gutierrez A, Carbonell JA, Aguilar G, Soro M, Belda FJ
BMC anesthesiology. 2014. 96. FI: 1.375
In response.
Ferrando C, Belda J
Anesthesia and analgesia. 2014 Nov. 1222-3. FI: 3.472
Setting individualized positive end-expiratory pressure level with a positive end-expiratory pressure decrement trial after a recruitment maneuver improves oxygenation and lung mechanics during one-lung ventilation.
Ferrando C, Mugarra A, Gutierrez A, Carbonell JA, García M, Soro M, Tusman G, Belda FJ
Anesthesia and analgesia. 2014 Mar. 657-65. FI: 3.472
Sevoflurane, but not propofol, reduces the lung inflammatory response and improves oxygenation in an acute respiratory distress syndrome model: a randomised laboratory study.
Ferrando C, Aguilar G, Piqueras L, Soro M, Moreno J, Belda FJ
European journal of anaesthesiology. 2013 Aug. 455-63. FI: 3.011
Intracranial hypertension related to sedation with sevoflurane using the AnaConDa(®) device in a patient with severe traumatic brain injury.
Ferrando C, Carbonell JA, Aguilar G, Badenes R, Belda FJ
Revista española de anestesiología y reanimación. 2013 Oct. 472-5
Extravascular lung water does not increase in hypovolemic patients after a fluid-loading protocol guided by the stroke volume variation.
Ferrando C, Aguilar G, Belda FJ
Critical care research and practice. 2012. 437659
Echinocandins in a critically ill patient during continuous venovenous renal replacement.
Aguilar G, Carbonell JA, Ferrando C, Badenes R, Belda FJ
Revista iberoamericana de micología. 2012 Apr. 85-9. FI: 1.312

Reducción de la complicaciones postoperatorias y de la estancia hospitalaria con una estrategia perioeratoria individualizada de ventilación de protección pulmonar.

Referencia:
PI14/00829
Investigador principal:
Carlos Ferrando Ortola
Entidad financiadora:
Instituto de Salud Carlos III
Duración:
01/01/2015 - 31/12/2017
Presupuesto total:
€108.250

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